Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958651 | 0.76 | NFE2L2 (0.56) | LMNACYP1A2CYP2C19KDM4EALDH1A1 | |
| SCHEMBL7528767 | 0.75 | PRMT5 (0.55) | PRMT5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL14786203 | 0.71 | LCK (0.77) | LCKMAOBLMNACYP1A2PTGS1 | |
| SCHEMBL20024692 | 0.71 | LCK (0.77) | LCKMAOBLMNACYP1A2PTGS1 | |
| SCHEMBL7958780 | 0.71 | LCK (0.48) | LCKMAOBLMNACYP1A2PTGS1 | |
| SCHEMBL10990566 | 0.71 | LMNA (0.59) | LCKMAOBLMNACYP1A2PTGS1 | |
| SCHEMBL27367676 | 0.71 | LMNA (0.82) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL339813 | 0.71 | LMNA (0.82) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL229009 | 0.71 | GRM5 (0.46) | PRMT5CYP2C19HDAC6ALDH1A1MAPT | |
| SCHEMBL29518247 | 0.71 | GRM5 (0.46) | PRMT5CYP2C19HDAC6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |