Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086460 | 0.81 | PRMT5 (0.53) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL29254767 | 0.81 | PRMT5 (0.53) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL7373015 | 0.79 | MCL1 (0.55) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL8615437 | 0.79 | RAB9A (0.57) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL8614763 | 0.79 | RAB9A (0.54) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL27743534 | 0.78 | CYP1A2 (0.61) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL6587114 | 0.77 | ENPP3 (0.55) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL7379345 | 0.77 | PRMT5 (0.59) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL8616299 | 0.76 | LMNA (0.53) | PRMT5RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL197017 | 0.76 | LMNA (0.72) | RAB9ASMN1; SMN2MEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099210-A1 | Propanoic acid derivatives as integrin inhibitors | CELLTECH CHIROSCIENCE LTD. (GB) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099210-A1 | Propanoic acid derivatives as integrin inhibitors | ITGA1, ITGB1, ITGB7 | PRMT5 3940/4885RAB9A 1587/4885SMN1; SMN2 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.