Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | RORB | Q92753 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974971 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL7974954 | 0.81 | TP53 (0.48) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL6578775 | 0.80 | RORA (0.45) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL6581975 | 0.80 | RORA (0.45) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL7974940 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL7974943 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL27387414 | 0.79 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL6576605 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL7964620 | 0.79 | CNR1 (0.53) | KDM4EALDH1A1HPGDHSD17B10CNR2 | |
| SCHEMBL7974921 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |