Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576521 | 0.91 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7974943 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7974940 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6579398 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7974971 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7978061 | 0.80 | GSK3B (0.42) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7974954 | 0.79 | TP53 (0.48) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL6280815 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7974952 | 0.79 | RORA (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL347395 | 0.78 | LTA4H (0.50) | KDM4EALDH1A1HPGDHSD17B10NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |