SCHEMBL7975102

SCHEMBL7975102

CC(=O)c1cc(Cc2ccc(Cl)nc2)co1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
KMT2A Q03164 4/20 0.43
MEN1 O00255 1/20 0.43
ATM Q13315 1/20 0.43
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
LMNA P02545 1/20 0.37
MAPT P10636 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 2/20 0.36
KDM4E B2RXH2 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975099 0.76 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL12764890 0.70 ALDH1A1 (0.62) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL18756583 0.69 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL5717114 0.67 ALDH1A1 (0.58) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL2632301 0.66 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL2134732 0.66 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL1747868 0.66 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL29811285 0.66 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1ATMRAB9A
Butanone SCHEMBL28417897 0.66 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL9480652 0.66 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1ATMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed