Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | VHL | P40337 | 1/20 | 0.46 |
| ▸ | BPTF | Q12830 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29811285 | 1.00 | ALDH1A1 (0.57) | ALDH1A1FAAHL3MBTL1MAPTKDM4E | |
| SCHEMBL3704245 | 0.84 | L3MBTL1 (0.56) | ALDH1A1FAAHL3MBTL1MAPTKDM4E | |
| SCHEMBL5012151 | 0.83 | FAAH (0.61) | ALDH1A1FAAHL3MBTL1MAPTKDM4E | |
| SCHEMBL255686 | 0.83 | KDM4E (0.56) | ALDH1A1MAPTKDM4EKMT2ARAB9A | |
| SCHEMBL763479 | 0.83 | KDM4E (0.51) | ALDH1A1FAAHL3MBTL1MAPTKDM4E | |
| SCHEMBL625919 | 0.83 | CYP2C9 (0.61) | ALDH1A1FAAHL3MBTL1MAPTKDM4E | |
| SCHEMBL27799938 | 0.82 | NAMPT (0.53) | ALDH1A1FAAHL3MBTL1MAPTKDM4E | |
| SCHEMBL19323949 | 0.82 | ALDH1A1 (0.53) | ALDH1A1FAAHL3MBTL1MAPTKDM4E | |
| SCHEMBL24016013 | 0.81 | KMT2A (0.51) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL3604595 | 0.81 | KMT2A (0.51) | ALDH1A1MAPTKDM4EKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249821-A1 | NOVEL ARGINASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-12-17 | — | — | WO | disclosed |
| EP-2719688-B1 | Process for producing tetrazolyloxime derivatives | NIPPON SODA CO (JP) | 2016-07-20 | — | — | EP | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| US-9212148-B2 | Functionalizing reagents and their uses | GLYTHERA LIMITED (GB) | 2015-12-15 | — | — | US | disclosed |
| EP-2719686-B1 | Process to halogenate a picoline derivative | NIPPON SODA CO (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-2373675-B1 | THIOL-FUNCTIONALISING REAGENTS AND THEIR USES | GLYTHERA LTD (GB) | 2015-10-21 | — | — | EP | disclosed |
| EP-2719687-B1 | Process to make a bromopicoline derivative | NIPPON SODA CO (JP) | 2015-09-16 | — | — | EP | disclosed |
| EP-2886132-A1 | Thiol-functionalising reagents and their uses | Glythera Limited (GB) | 2015-06-24 | — | — | EP | disclosed |
| US-9018385-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9012653-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| EP-2546236-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | Nippon Soda Co., Ltd. (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20130012713-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD | 2013-01-10 | — | — | US | disclosed |
| US-20120101254-A1 | FUNCTIONALISING REAGENTS AND THEIR USES | Iksuda Therapeutics Limited (GB) | 2012-04-26 | — | — | US | disclosed |
| WO-2010070300-A2 | FUNCTIONALISING REAGENTS AND THEIR USES | THE UNIVERSITY OF BATH (GB) | 2010-06-24 | — | — | WO | disclosed |
| EP-0722933-B1 | Process for the preparation of chloromethylpyridine derivatives and acylaminomethyl pyridines as intermediates | BAYER AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| EP-0691331-B1 | Process for the preparation of n-acylated 2-chloro-5-aminomethyl-pyridines | BAYER AG (DE) | 2001-10-10 | — | — | EP | disclosed |
| US-5623076-A | Process for the preparation of chloromethylpyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| US-5580983-A | Process for the preparation of N-acylated 2-chloro-5-aminomethylpyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| EP-0722933-A1 | Process for the preparation of chloromethylpyridine derivatives and acylaminomethyl pyridines as intermediates | BAYER AG (DE) | 1996-07-24 | — | — | EP | disclosed |
| EP-0691331-A1 | Process for the preparation of n-acylated 2-chloro-5-aminomethyl-pyridines | BAYER AG (DE) | 1996-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101254-A1 | FUNCTIONALISING REAGENTS AND THEIR USES | VNN1, FGB, LNPEP | ALDH1A1 2427/4885FAAH 1900/4885L3MBTL1 2965/4885 |
| US-20130012713-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | CBR3, PNPO, AADAC | ALDH1A1 1365/4885FAAH 4209/4885L3MBTL1 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.