Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 6/20 | 0.42 |
| ▸ | F12 | P00748 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989587 | 0.88 | ADORA1 (0.46) | ADORA1C5AR1F12ESR2MAPT | |
| SCHEMBL29574016 | 0.82 | C5AR1 (0.42) | ADORA1C5AR1F12ESR2MAPT | |
| SCHEMBL1007338 | 0.80 | TRPM2 (0.45) | ADORA1MAPTCYP2C19TRPM2 | |
| SCHEMBL31700101 | 0.80 | ADORA1 (0.51) | ADORA1C5AR1F12ESR2MAPT | |
| SCHEMBL22716373 | 0.78 | ADORA1 (0.43) | ADORA1C5AR1F12ESR2MAPT | |
| SCHEMBL1885657 | 0.78 | F12 (0.57) | ADORA1C5AR1F12ESR2MAPT | |
| SCHEMBL22718671 | 0.78 | ADORA1 (0.46) | ADORA1C5AR1F12ESR2MAPT | |
| SCHEMBL7988759 | 0.78 | KMT2A (0.50) | ADORA1C5AR1ESR2MAPTNR1H2 | |
| SCHEMBL31700014 | 0.78 | ADORA1 (0.49) | ADORA1C5AR1F12ESR2MAPT | |
| SCHEMBL7975140 | 0.78 | ESR2 (0.44) | ADORA1ESR2MAPTNR1H2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |