Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988759 | 0.80 | KMT2A (0.50) | ESR2NR1H2ADORA1MAPK1MAPT | |
| SCHEMBL7975140 | 0.77 | ESR2 (0.44) | ESR2NR1H2ADORA1MAPK1MAPT | |
| SCHEMBL7986411 | 0.76 | ESR2 (0.58) | ESR2NR1H2ADORA1MAPK1MAPT | |
| SCHEMBL19642983 | 0.74 | ESR2 (0.60) | ESR2NR1H2ADORA1MAPK1HDAC1 | |
| SCHEMBL5849968 | 0.74 | MAPK1 (0.49) | ESR2NR1H2MAPK1MAPTL3MBTL1 | |
| SCHEMBL1648607 | 0.73 | NR1H2 (0.63) | ESR2NR1H2ADORA1MAPK1MAPT | |
| SCHEMBL31337577 | 0.73 | ESR2 (0.65) | ESR2NR1H2ADORA1MAPK1MAPT | |
| SCHEMBL30583454 | 0.73 | NR1H2 (0.63) | ESR2NR1H2ADORA1MAPK1MAPT | |
| SCHEMBL30583396 | 0.73 | ESR2 (0.65) | ESR2NR1H2ADORA1MAPK1MAPT | |
| SCHEMBL19641653 | 0.73 | ESR2 (0.57) | ESR2NR1H2ADORA1MAPK1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |