SCHEMBL7975148

SCHEMBL7975148

O=CC(OCc1ccccc1)c1cncc(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
SLC6A4 P31645 3/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
P2RX7 Q99572 1/20 0.36
SLC1A3 P43003 2/20 0.35
SLC1A2 P43004 2/20 0.35
SLC1A1 P43005 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
PLAU P00749 1/20 0.34
PTGER1 P34995 4/20 0.34
MAPT P10636 1/20 0.34
TBXA2R P21731 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467072 0.77 SLC1A3 (0.46) IDO1CHRNB2CHRNA4SLC6A4SLC6A2
SCHEMBL9025351 0.77 SLC1A3 (0.46) IDO1CHRNB2CHRNA4SLC6A4SLC6A2
SCHEMBL22164377 0.70 ALDH1A1 (0.39) IDO1CHRNB2CHRNA4SLC6A4SLC6A2
SCHEMBL7958440 0.69 SLC1A3 (0.40) IDO1CHRNB2CHRNA4SLC6A4SLC6A2
SCHEMBL28451883 0.69 AOC3 (0.53) KMT2AMEN1
SCHEMBL7057444 0.67 CHRNB2 (0.49) CHRNB2CHRNA4SLC6A4SLC6A2SLC6A3
SCHEMBL1822250 0.67 TDP1 (0.47) KMT2AMEN1MAPT
SCHEMBL8444196 0.66 HCAR2 (0.40) IDO1SLC6A4SLC6A2SLC6A3
SCHEMBL6147663 0.66 RXRA (0.43) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL27668092 0.66 ESR1 (0.44) KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed