Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.45 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.44 |
| ▸ | PARN | O95453 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975265 | 0.93 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 | |
| SCHEMBL8056885 | 0.89 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDGRK2 | |
| SCHEMBL7991672 | 0.88 | CNOT7 (0.46) | ALDH1A1SMN1; SMN2KMT2AHPGDMAPT | |
| SCHEMBL7985823 | 0.88 | HPGD (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDMAPT | |
| SCHEMBL7985270 | 0.88 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDGRIA1 | |
| SCHEMBL7975129 | 0.88 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2KMT2AHPGDMAPT | |
| SCHEMBL7984453 | 0.88 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 | |
| SCHEMBL7974283 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDMAPT | |
| SCHEMBL7974505 | 0.87 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 | |
| SCHEMBL7988556 | 0.87 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |