Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662732 | 0.95 | PDCD1 (0.43) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL28481345 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7977434 | 0.84 | L3MBTL1 (0.43) | ALDH1A1KDM4ESMN1; SMN2LMNAPOLB | |
| SCHEMBL18090997 | 0.80 | SMN1; SMN2 (0.57) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL3903483 | 0.80 | PDCD1 (0.44) | KMT2AMEN1LMNARAB9APDCD1 | |
| SCHEMBL16955136 | 0.80 | PDCD1 (0.44) | ALDH1A1KDM4EPDCD1CD274L3MBTL1 | |
| SCHEMBL19167836 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4ESMN1; SMN2LMNAPOLB | |
| SCHEMBL30507629 | 0.79 | KDM4E (0.43) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL1053518 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1KDM4ESMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7997520 | 0.79 | HTR1B (0.50) | KDM4ESMN1; SMN2RAB9APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |