Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955136 | 0.84 | PDCD1 (0.44) | HTR1BKDM4EHPGDMAPK1PDCD1 | |
| SCHEMBL7997617 | 0.83 | PDCD1 (0.43) | HTR1BKDM4ESMN1; SMN2MAPK1TP53 | |
| SCHEMBL1662732 | 0.83 | PDCD1 (0.43) | HTR1BKDM4EMAPK1PDCD1CD274 | |
| SCHEMBL10000453 | 0.82 | KDM4E (0.63) | HTR1BKDM4EHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL2354192 | 0.80 | PDCD1 (0.47) | KDM4EMAPK1PDCD1CD274MAPT | |
| SCHEMBL7975336 | 0.79 | ALDH1A1 (0.44) | HTR1BKDM4ESMN1; SMN2RAB9APDCD1 | |
| SCHEMBL7148420 | 0.79 | SMN1; SMN2 (0.43) | HTR1BKDM4EHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL7415579 | 0.78 | HTR1B (0.62) | HTR1BKDM4EHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL3903483 | 0.77 | PDCD1 (0.44) | HTR1BMAPK1RAB9APDCD1CD274 | |
| SCHEMBL13117549 | 0.77 | CD274 (0.57) | HTR1BKDM4ESMN1; SMN2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |