Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975340 | 1.00 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7974395 | 0.94 | POLB (0.45) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7977473 | 0.88 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7980407 | 0.86 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7974453 | 0.85 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7974403 | 0.85 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7974397 | 0.84 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7974298 | 0.83 | POLB (0.50) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7975339 | 0.82 | AR (0.49) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7964041 | 0.81 | POLB (0.47) | RAB9ANPC1SMN1; SMN2LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |