Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975339 | 0.93 | AR (0.49) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7980374 | 0.93 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7974403 | 0.92 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7975324 | 0.90 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7974453 | 0.88 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7974397 | 0.88 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7974298 | 0.87 | POLB (0.50) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7964005 | 0.86 | POLB (0.46) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7975337 | 0.86 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2LMNARECQL | |
| SCHEMBL7975340 | 0.86 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |