Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | UBE2N | P61088 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988218 | 0.86 | HPGD (0.40) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL7081396 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1UBE2NKMT2AMEN1 | |
| SCHEMBL7975780 | 0.79 | EPHX1 (0.32) | SMN1; SMN2ALDH1A1UBE2NGAALMNA | |
| SCHEMBL7988689 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1GAACYP2C19HPGD | |
| SCHEMBL6564601 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL7993433 | 0.77 | HTT (0.32) | SMN1; SMN2ALDH1A1KMT2AHTTCYP2C19 | |
| SCHEMBL7992134 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL10817380 | 0.76 | PRSS1 (0.33) | KMT2A | |
| SCHEMBL7992447 | 0.75 | L3MBTL1 (0.38) | SMN1; SMN2ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL7985973 | 0.73 | HSD17B10 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |