Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974910 | 0.86 | HPGD (0.38) | ALDH1A1LMNAHPGDALOX15SMN1; SMN2 | |
| SCHEMBL7988689 | 0.84 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2MASP2 | |
| SCHEMBL7986256 | 0.84 | NFKB1 (0.36) | SMN1; SMN2MAPT | |
| SCHEMBL7988673 | 0.84 | TSHR (0.38) | ALDH1A1LMNAHPGDS1PR3SMN1; SMN2 | |
| SCHEMBL7988304 | 0.84 | SMN1; SMN2 (0.44) | ALDH1A1LMNAHPGDALOX15S1PR3 | |
| SCHEMBL7985973 | 0.83 | HSD17B10 (0.31) | HSD17B10TDP1 | |
| SCHEMBL7975780 | 0.82 | EPHX1 (0.32) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7986464 | 0.82 | MASP2 (0.40) | ALDH1A1LMNAALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL7989908 | 0.82 | CYP3A4 (0.32) | ALOX15TSHR | |
| SCHEMBL7992134 | 0.82 | SMN1; SMN2 (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | MERCK PATENT GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | F11, F2, F12 | ALDH1A1 471/4885LMNA 4134/4885HPGD 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.