Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.33 |
| ▸ | MICA | Q29983 | 1/20 | 0.33 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975406 | 1.00 | MAPT (0.38) | MAPTNPSR1MAPK1KDM4EADRB1 | |
| SCHEMBL7963988 | 0.96 | MAPT (0.37) | MAPTNPSR1MAPK1KDM4EADRB1 | |
| SCHEMBL7963987 | 0.88 | ADRB1 (0.39) | MAPTNPSR1MAPK1KDM4EADRB1 | |
| SCHEMBL7963984 | 0.88 | ADRB1 (0.39) | MAPTNPSR1MAPK1KDM4EADRB1 | |
| SCHEMBL6435848 | 0.81 | ADRB1 (0.45) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6432460 | 0.81 | ADRB3 (0.52) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6432465 | 0.81 | ADRB3 (0.52) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6436877 | 0.81 | MCHR1 (0.40) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6436884 | 0.81 | MCHR1 (0.40) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6435843 | 0.81 | ADRB1 (0.43) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042217-A1 | BETA-3 ADRENOCEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |