Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978676 | 0.83 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2APKMMAPK1 | |
| SCHEMBL7978818 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7978610 | 0.78 | ALDH1A1 (0.45) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7978680 | 0.78 | L3MBTL1 (0.73) | MAPTALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL7978822 | 0.76 | L3MBTL1 (0.54) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12309829 | 0.75 | MAPT (0.49) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7976975 | 0.75 | L3MBTL1 (0.55) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL7976868 | 0.73 | KMT2A (0.47) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7976858 | 0.73 | L3MBTL1 (0.61) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL30023041 | 0.72 | HPGD (0.59) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |