Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978676 | 0.86 | ALDH1A1 (0.52) | KMT2AL3MBTL1GAAMAPK1ALDH1A1 | |
| SCHEMBL7981607 | 0.83 | L3MBTL1 (0.54) | KMT2AL3MBTL1GAALMNAALDH1A1 | |
| SCHEMBL7976858 | 0.81 | L3MBTL1 (0.61) | KMT2AL3MBTL1GAAMAPK1LMNA | |
| SCHEMBL7978680 | 0.81 | L3MBTL1 (0.73) | KMT2AL3MBTL1GAALMNAALDH1A1 | |
| SCHEMBL7976975 | 0.81 | L3MBTL1 (0.55) | KMT2AL3MBTL1GAALMNAALDH1A1 | |
| SCHEMBL7978822 | 0.80 | L3MBTL1 (0.54) | KMT2AL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL12309829 | 0.79 | MAPT (0.49) | KMT2AL3MBTL1GAALMNAALDH1A1 | |
| SCHEMBL7965237 | 0.76 | L3MBTL1 (0.55) | KMT2AL3MBTL1GAALMNAALDH1A1 | |
| SCHEMBL11090178 | 0.76 | ALDH1A1 (0.49) | KMT2AGAALMNAALDH1A1MAPT | |
| SCHEMBL7978818 | 0.74 | ALDH1A1 (0.51) | KMT2AL3MBTL1GAAMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |