Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27109390 | 1.00 | TSHR (0.48) | TSHRSLC1A1MGAMGAASI | |
| SCHEMBL19487360 | 1.00 | TSHR (0.48) | TSHRSLC1A1MGAMGAASI | |
| SCHEMBL17817738 | 0.83 | SLC1A1 (0.49) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL15180397 | 0.83 | TSHR (0.48) | TSHRSLC1A1MGAMGAASI | |
| SCHEMBL13790646 | 0.83 | SLC1A1 (0.49) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL24445692 | 0.83 | TSHR (0.48) | TSHRSLC1A1MGAMGAASI | |
| SCHEMBL8288900 | 0.82 | L3MBTL1 (0.57) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL797542 | 0.82 | L3MBTL1 (0.57) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL25530071 | 0.82 | L3MBTL1 (0.38) | TSHRKMT2AL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL13790912 | 0.82 | TSHR (0.46) | TSHRSLC1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073622-A2 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF | RAYZEBIO, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| US-8933030-B2 | Treatments for gastrointestinal disorders | Ironwwod Pharmaceuticals, Inc. (US) | 2015-01-13 | — | — | US | disclosed |
| US-8911710-B2 | Intravascular contrast agents | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-12-16 | — | — | US | disclosed |
| US-20140073571-A9 | Treatments for Gastrointestinal Disorders | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2014-03-13 | — | — | US | disclosed |
| US-20130190238-A1 | Treatments for Gastrointestinal Disorders | FRETZEN ANGELIKA (US) | 2013-07-25 | — | — | US | disclosed |
| US-20120071612-A1 | METHOD FOR THE PRODUCTION OF POLYAMINO ACID RANDOM COPOLYMERS | SIGMA-ALDRICH CO., LLC (US) | 2012-03-22 | — | — | US | disclosed |
| US-20090306228-A1 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | SHIRE LLC (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190238-A1 | Treatments for Gastrointestinal Disorders | GRPR, GIPR, GCGR | TSHR 1054/4885SLC1A1 4237/4885MGAM 1255/4885 |
| US-20090306228-A1 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | HDGF, CTSA, IAPP | TSHR 1777/4885SLC1A1 919/4885MGAM 2491/4885 |
| US-20140073571-A9 | Treatments for Gastrointestinal Disorders | GRPR, GIPR, GCGR | TSHR 1054/4885SLC1A1 4237/4885MGAM 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.