Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288900 | 1.00 | L3MBTL1 (0.57) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL13108405 | 0.87 | L3MBTL1 (0.69) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL13099456 | 0.87 | L3MBTL1 (0.69) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL15132262 | 0.86 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL28539938 | 0.85 | L3MBTL1 (0.57) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL25660778 | 0.85 | L3MBTL1 (0.57) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL25530065 | 0.85 | ALDH1A1 (0.46) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL18806449 | 0.83 | DGKA (0.44) | L3MBTL1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL797557 | 0.82 | TSHR (0.48) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL19487360 | 0.82 | TSHR (0.48) | L3MBTL1KMT2APOLBGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-28 | — | — | US | disclosed |
| US-9243040-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-26 | — | — | US | disclosed |
| US-8933030-B2 | Treatments for gastrointestinal disorders | Ironwwod Pharmaceuticals, Inc. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140073571-A9 | Treatments for Gastrointestinal Disorders | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2014-03-13 | — | — | US | disclosed |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130190238-A1 | Treatments for Gastrointestinal Disorders | FRETZEN ANGELIKA (US) | 2013-07-25 | — | — | US | disclosed |
| US-20120071612-A1 | METHOD FOR THE PRODUCTION OF POLYAMINO ACID RANDOM COPOLYMERS | SIGMA-ALDRICH CO., LLC (US) | 2012-03-22 | — | — | US | disclosed |
| US-7317070-B1 | Process for the preparation of polyamino acids | SIGMA-ALDRICH CO. (US) | 2008-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190238-A1 | Treatments for Gastrointestinal Disorders | GRPR, GIPR, GCGR | L3MBTL1 3979/4885KMT2A 4865/4885POLB 2926/4885 |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | L3MBTL1 2681/4885KMT2A 4638/4885POLB 1696/4885 |
| US-20140073571-A9 | Treatments for Gastrointestinal Disorders | GRPR, GIPR, GCGR | L3MBTL1 3979/4885KMT2A 4865/4885POLB 2926/4885 |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | L3MBTL1 2681/4885KMT2A 4638/4885POLB 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.