Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962153 | 0.98 | MAPT (0.41) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL11552403 | 0.86 | ALDH1A1 (0.40) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL11549097 | 0.84 | HPGD (0.39) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL28175738 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1819086 | 0.79 | MAPT (0.61) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL6331933 | 0.76 | MAPT (0.62) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL8710504 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL11402027 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL21138457 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL11488922 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281295-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2001-08-28 | — | — | US | claimed |
| US-6281295-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2001-08-28 | — | — | US | disclosed |
| EP-0735083-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL EUROP (CH) | 2000-02-09 | — | — | EP | disclosed |
| EP-0735083-A1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1996-10-02 | — | — | EP | disclosed |