Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508911 | 0.92 | HSP90AA1 (0.38) | HSP90AA1IDO1AGXTARCACNA1G | |
| SCHEMBL7989604 | 0.90 | CA1 (0.42) | HSP90AA1MEN1KMT2ATP53GAA | |
| SCHEMBL7992780 | 0.87 | IDO1 (0.41) | HSP90AA1IDO1AGXTARMAOB | |
| SCHEMBL7987648 | 0.85 | HSP90AA1 (0.39) | HSP90AA1IDO1MAOBMEN1KMT2A | |
| SCHEMBL7985912 | 0.84 | CA1 (0.45) | HSP90AA1MEN1KMT2ATP53GAA | |
| SCHEMBL7509873 | 0.84 | HSP90AA1 (0.38) | HSP90AA1IDO1AGXTARMAOB | |
| SCHEMBL7989942 | 0.84 | CA1 (0.47) | HSP90AA1MEN1KMT2ATP53GAA | |
| SCHEMBL7989889 | 0.84 | CA1 (0.47) | HSP90AA1MEN1KMT2ATP53GAA | |
| SCHEMBL7509273 | 0.84 | CA1 (0.47) | HSP90AA1MEN1KMT2ATP53GAA | |
| SCHEMBL7987303 | 0.83 | HSP90AA1 (0.43) | HSP90AA1IDO1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |