SCHEMBL7987648

SCHEMBL7987648

O[C@@H]([C@H](O)[C@@H](COCc1ccccc1F)OCc1ccc(F)cc1)[C@@H](COCc1ccccc1F)OCc1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.39
IDO1 P14902 2/20 0.38
MAOB P27338 4/20 0.38
ALDH1A1 P00352 3/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CHRM3 P20309 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
SLC6A4 P31645 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
TRPV6 Q9H1D0 1/20 0.34
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7987303 0.97 HSP90AA1 (0.43) HSP90AA1IDO1MAOBALDH1A1PKM
SCHEMBL7447822 0.96 HSP90AA1 (0.44) HSP90AA1IDO1MAOBCHRM3CA1
SCHEMBL7989824 0.92 ALDH1A1 (0.39) IDO1MAOBALDH1A1PKMCA1
SCHEMBL7989289 0.92 CA1 (0.42) HSP90AA1IDO1MAOBALDH1A1CA1
SCHEMBL7989311 0.90 CA1 (0.44) HSP90AA1IDO1ALDH1A1CA1CA2
SCHEMBL7989863 0.90 IDO1 (0.36) IDO1MAOBALDH1A1SMN1; SMN2LMNA
SCHEMBL7986153 0.90 LMNA (0.39) IDO1MAOBALDH1A1LMNAKDM4E
SCHEMBL7510667 0.89 NPSR1 (0.39) HSP90AA1ALDH1A1SMN1; SMN2KDM4EGAA
SCHEMBL7509873 0.88 HSP90AA1 (0.38) HSP90AA1IDO1MAOBALDH1A1PKM
SCHEMBL7509426 0.88 MPO (0.41) HSP90AA1IDO1MAOBALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313177-B1 AS ANTIVIRAL AGENTS PHARMACOR INC. (CA) 2001-11-06 US disclosed