SCHEMBL7987303

SCHEMBL7987303

O[C@@H]([C@H](O)[C@@H](COCc1ccccc1F)OCc1ccc(F)cc1)[C@@H](COCc1ccccc1F)OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.43
CA1 P00915 3/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
IDO1 P14902 2/20 0.36
CHRM3 P20309 1/20 0.36
MAOB P27338 3/20 0.36
LPAR1 Q92633 1/20 0.35
LPAR5 Q9H1C0 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PTPN1 P18031 1/20 0.34
ALDH1A1 P00352 2/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7447822 0.99 HSP90AA1 (0.44) HSP90AA1CA1CA2CA7CA9
SCHEMBL7987648 0.97 HSP90AA1 (0.39) HSP90AA1CA1CA2CA7CA9
SCHEMBL7989289 0.95 CA1 (0.42) HSP90AA1CA1CA2CA7CA9
SCHEMBL7989311 0.93 CA1 (0.44) HSP90AA1CA1CA2CA7CA9
SCHEMBL7989824 0.90 ALDH1A1 (0.39) CA1CA2CA7CA9MEN1
SCHEMBL7976011 0.89 CA1 (0.45) HSP90AA1CA1CA2CA7CA9
SCHEMBL7456440 0.89 MAOB (0.46) MEN1KMT2AMAOBLPAR1LPAR5
SCHEMBL7509273 0.89 CA1 (0.47) HSP90AA1CA1CA2CA7CA9
SCHEMBL7989889 0.89 CA1 (0.47) HSP90AA1CA1CA2CA7CA9
SCHEMBL7989942 0.89 CA1 (0.47) HSP90AA1CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313177-B1 AS ANTIVIRAL AGENTS PHARMACOR INC. (CA) 2001-11-06 US disclosed