Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | AGXT | P21549 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987648 | 0.88 | HSP90AA1 (0.39) | HSP90AA1KDM4EL3MBTL1MAOBTDP1 | |
| SCHEMBL7987303 | 0.86 | HSP90AA1 (0.43) | HSP90AA1KDM4EMAOBTDP1IDO1 | |
| SCHEMBL7447822 | 0.85 | HSP90AA1 (0.44) | HSP90AA1KDM4EL3MBTL1MAOBIDO1 | |
| SCHEMBL7509426 | 0.85 | MPO (0.41) | HSP90AA1KDM4EL3MBTL1MAOBTDP1 | |
| SCHEMBL7975690 | 0.84 | HSP90AA1 (0.40) | HSP90AA1MAOBARIDO1AGXT | |
| SCHEMBL7989824 | 0.83 | ALDH1A1 (0.39) | KDM4EL3MBTL1MAOBIDO1ALDH1A1 | |
| SCHEMBL7510838 | 0.83 | KDM4E (0.36) | HSP90AA1KDM4EL3MBTL1MAOBTDP1 | |
| SCHEMBL7508911 | 0.82 | HSP90AA1 (0.38) | HSP90AA1KDM4EL3MBTL1MAOBTDP1 | |
| SCHEMBL7992780 | 0.82 | IDO1 (0.41) | HSP90AA1MAOBARIDO1AGXT | |
| SCHEMBL7990123 | 0.81 | ESR1 (0.39) | HSP90AA1KDM4EL3MBTL1TDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |