⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292973 | 0.71 | — | — | |
| SCHEMBL10029199 | 0.67 | — | — | |
| SCHEMBL18331668 | 0.61 | — | — | |
| SCHEMBL8786345 | 0.60 | ADH1B (0.42) | — | |
| SCHEMBL8568538 | 0.60 | GAA (0.42) | — | |
| SCHEMBL539827 | 0.58 | — | — | |
| SCHEMBL22403870 | 0.58 | L3MBTL1 (0.34) | — | |
| SCHEMBL10548279 | 0.57 | — | — | |
| SCHEMBL21707535 | 0.57 | ALDH1A1 (0.36) | — | |
| SCHEMBL26656335 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023222124-A1 | 5,6-DIHYDRO-1,2,4-TRIAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF AS GLP-1 RECEPTOR AGONIST | 中国科学院上海药物研究所 | 2023-11-23 | — | — | WO | disclosed |
| CN-109265400-B | Arginine methyltransferase inhibitors and uses thereof | EPIZYME股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-6214826-B1 | NERVOUS SYSTEM DISORDERS | ZENECA LIMITED (GB) | 2001-04-10 | — | — | US | disclosed |
| CN-1102643-A | Substituted derivatives of diaminophthalimide | CIBA GEIGY AG (CH) | 1995-05-17 | — | — | CN | disclosed |