SCHEMBL7975870

SCHEMBL7975870

CCOc1[c]ccc(C(=N)N)c1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 17/20 0.50
PRSS2 P07478 2/20 0.50
PRSS3 P35030 2/20 0.50
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
F7 P08709 1/20 0.39
PLAU P00749 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7985574 0.81 PRSS1 (0.49) PRSS1PRSS2PRSS3F10PLAU
SCHEMBL4949888 0.78 TSHR (0.49)
SCHEMBL8174623 0.77 F2 (0.46) PRSS1PRSS2PRSS3F2F10
SCHEMBL8173720 0.76 PRSS1 (0.37) PRSS1F2F10PLAU
SCHEMBL8170377 0.76 F2 (0.44) PRSS1PRSS2PRSS3F2
SCHEMBL8174922 0.74 NFE2L2 (0.40) PRSS1PRSS2PRSS3F2F10
SCHEMBL7985427 0.74 PRSS1 (0.41) PRSS1PRSS2PRSS3F2PLAU
SCHEMBL6602231 0.73 TP53 (0.46)
SCHEMBL3048684 0.73 LTA4H (0.38)
SCHEMBL8163805 0.72 F10 (0.47) F2F10PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed