Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726132 | 0.83 | ALDH1A1 (0.46) | CYP2D6CYP2C9CYP2C19KMT2AMTNR1A | |
| SCHEMBL7975973 | 0.72 | MRGPRX4 (0.35) | SLC6A2HTR2AHTR2CHTR2BPLAAT3 | |
| SCHEMBL31504505 | 0.69 | TAAR1 (0.49) | CASRHTR1AADRA2BADRA2CSLC6A2 | |
| SCHEMBL5725348 | 0.69 | ALDH1A1 (0.44) | KMT2AHDAC8PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL26622159 | 0.64 | SLC6A2 (0.46) | CASRSLC6A2HDAC8HIF1APLAAT3 | |
| SCHEMBL9767859 | 0.62 | SLC6A2 (0.51) | KMT2ASLC6A2HIF1APLAAT3PLAAT5 | |
| SCHEMBL31688712 | 0.62 | FOLH1 (0.48) | CASRSLC6A2HIF1APLAAT3PLAAT5 | |
| SCHEMBL26622161 | 0.62 | TAAR1 (0.50) | CASRHIF1APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9064570 | 0.61 | PTGER1 (0.62) | KMT2AHTR1AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL261238 | 0.61 | POLB (0.54) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |