Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.59 |
| ▸ | PLG | P00747 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 3/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971563 | 0.91 | KAT6A (0.53) | KAT6APLGMMP9NPY5RF10 | |
| SCHEMBL7960292 | 0.87 | MMP9 (0.62) | KAT6AMMP9MMP2TACR1 | |
| SCHEMBL7959981 | 0.85 | NPY5R (0.55) | PLGMMP9NPY5RMMP2F2 | |
| SCHEMBL31086902 | 0.85 | MMP2 (0.73) | MMP9NPY5RMMP2F2POLB | |
| SCHEMBL3310154 | 0.83 | MMP2 (0.71) | MMP9NPY5RMMP2F2POLB | |
| SCHEMBL31086814 | 0.83 | MMP2 (0.71) | MMP9NPY5RMMP2F2POLB | |
| SCHEMBL7290941 | 0.83 | MMP2 (0.71) | MMP9NPY5RMMP2F2POLB | |
| SCHEMBL5189194 | 0.83 | MMP2 (0.71) | MMP9NPY5RMMP2F2POLB | |
| SCHEMBL10830546 | 0.81 | F2 (0.58) | PLGMMP9NPY5RMMP2F2 | |
| SCHEMBL5780617 | 0.81 | F2 (0.61) | PLGMMP9NPY5RF10PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |