Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976144 | 0.91 | KAT6A (0.59) | KAT6AMMP9MMP2F2POLB | |
| SCHEMBL7976158 | 0.90 | MMP9 (0.58) | KAT6AMMP9MMP2POLBCA2 | |
| SCHEMBL7971077 | 0.87 | MMP9 (0.53) | MMP9MMP2F2POLBMMP1 | |
| SCHEMBL8647491 | 0.86 | MMP2 (0.69) | MMP9MMP2F2POLBMMP1 | |
| SCHEMBL8389137 | 0.86 | MMP2 (0.69) | MMP9MMP2F2POLBMMP1 | |
| SCHEMBL7960292 | 0.79 | MMP9 (0.62) | KAT6AMMP9MMP2MMP1MMP13 | |
| SCHEMBL8118400 | 0.78 | TACR1 (0.61) | POLBMMP1PTPN1CA2 | |
| SCHEMBL6021666 | 0.78 | CTSS (0.58) | MMP9MMP2POLBMMP1MMP13 | |
| SCHEMBL3088714 | 0.77 | KDM4E (0.58) | KAT6AMMP9MMP2F2POLB | |
| SCHEMBL7984105 | 0.77 | BACE1 (0.62) | F2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |