Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596736 | 0.94 | FTO (0.69) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL15658275 | 0.89 | FTO (0.71) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL2152787 | 0.88 | FTO (0.64) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL13537269 | 0.88 | FTO (0.69) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL9428406 | 0.87 | FTO (0.74) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL29660490 | 0.87 | FTO (0.74) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL29406840 | 0.87 | FTO (0.78) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL25103 | 0.87 | FTO (0.78) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL17970938 | 0.87 | FTO (0.74) | FTOHPGDMEN1MAPTCYP2C19 | |
| SCHEMBL9626320 | 0.87 | FTO (0.74) | FTOHPGDMEN1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |