Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962531 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BF2LMNAPOLB | |
| SCHEMBL7962544 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL7972452 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL6975938 | 0.81 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL7085479 | 0.81 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL7391723 | 0.79 | ITGB3 (0.79) | ITGB3ITGA2BF2 | |
| SCHEMBL9397091 | 0.77 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL6978255 | 0.77 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7390910 | 0.76 | ITGB3 (0.68) | ITGB3ITGA2BF2 | |
| SCHEMBL7962515 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268380-B1 | E.G., ETHYL BETA-((N-3(((4(AMINOIMINOMETHYL)PHENYL)AMINO)CARBONYL)PIPERIDY LCARBONYL)AMINO)-3-PYRIDINEPROPANOATE | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | claimed |
| WO-1994019341-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-01 | — | — | WO | claimed |
| US-6268380-B1 | E.G., ETHYL BETA-((N-3(((4(AMINOIMINOMETHYL)PHENYL)AMINO)CARBONYL)PIPERIDY LCARBONYL)AMINO)-3-PYRIDINEPROPANOATE | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | disclosed |