Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23297133 | 0.90 | MEN1 (0.37) | L3MBTL3L3MBTL1ACEMEN1KMT2A | |
| SCHEMBL788990 | 0.90 | MEN1 (0.37) | L3MBTL3L3MBTL1ACEMEN1KMT2A | |
| SCHEMBL23297156 | 0.90 | MEN1 (0.37) | L3MBTL3L3MBTL1ACEMEN1KMT2A | |
| SCHEMBL2598560 | 0.82 | CYP3A4 (0.38) | L3MBTL3L3MBTL1ACEMEN1KMT2A | |
| SCHEMBL797229 | 0.78 | FPR2 (0.49) | — | |
| SCHEMBL797228 | 0.78 | FPR2 (0.49) | — | |
| SCHEMBL30341931 | 0.77 | KMT2A (0.40) | L3MBTL3L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL15264280 | 0.76 | KDM5A (0.44) | KMT2APOLBGAA | |
| SCHEMBL23336233 | 0.76 | FPR2 (0.39) | — | |
| SCHEMBL4300916 | 0.76 | HSD11B1 (0.34) | PLA2G7HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616074-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037393-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2012-03-22 | — | — | WO | disclosed |