Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517768 | 0.83 | ALDH1A1 (0.50) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL29661436 | 0.83 | ALDH1A1 (0.50) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL6371735 | 0.81 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL7973475 | 0.81 | ATM (0.46) | TDP1ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL30954094 | 0.81 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL19927661 | 0.78 | ALDH1A1 (0.46) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL31757016 | 0.78 | ALDH1A1 (0.51) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL30801468 | 0.78 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL12458650 | 0.78 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL25273441 | 0.77 | LMNA (0.47) | TDP1ALDH1A1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |