Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6084022 | 0.84 | VCAM1 (0.44) | ATMTDP1ALDH1A1KDM4EHTT | |
| SCHEMBL12919852 | 0.81 | PDK1 (0.39) | ATMTDP1ESPL1ALDH1A1HIF1A | |
| SCHEMBL7976359 | 0.81 | TDP1 (0.42) | TDP1ALDH1A1KDM4EHTTHCAR3 | |
| SCHEMBL4670199 | 0.81 | TDP1 (0.62) | ATMTDP1ESPL1ALDH1A1HIF1A | |
| SCHEMBL29559612 | 0.80 | MAPT (0.45) | ATMTDP1ESPL1ALDH1A1HIF1A | |
| SCHEMBL9427812 | 0.80 | ALDH3A1 (0.49) | ATMTDP1ESPL1ALDH1A1HIF1A | |
| SCHEMBL31423821 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EHTTHCAR3MAPT | |
| SCHEMBL58080 | 0.77 | TDP1 (0.58) | ATMTDP1ESPL1ALDH1A1HIF1A | |
| SCHEMBL29403879 | 0.77 | TDP1 (0.58) | ATMTDP1ESPL1ALDH1A1HIF1A | |
| SCHEMBL27076095 | 0.77 | ALDH1A1 (0.44) | ATMTDP1ALDH1A1HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |