Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965793 | 0.92 | HTT (0.39) | HTTTP53MAPK1GAAALDH1A1 | |
| SCHEMBL7965926 | 0.91 | HTT (0.39) | HTTTP53MAPK1GAAALDH1A1 | |
| SCHEMBL7976320 | 0.88 | HTT (0.40) | HTTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL8629077 | 0.88 | SCN8A (0.40) | HTTTP53MAPK1GAAALDH1A1 | |
| SCHEMBL7979221 | 0.87 | HTT (0.42) | HTTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL7979566 | 0.84 | SCN8A (0.43) | HTTCYP3A4KCNH2CACNA1CSCN5A | |
| SCHEMBL7965701 | 0.84 | HTT (0.37) | HTTGAAMEN1KMT2ADRD2 | |
| SCHEMBL7976122 | 0.84 | HTT (0.36) | HTTTP53MAPK1GAAKDM4E | |
| SCHEMBL7977787 | 0.84 | HTT (0.40) | HTTMAPK1GAAALDH1A1KDM4E | |
| SCHEMBL8661536 | 0.83 | HTT (0.43) | HTTTP53GAAALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |