Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988498 | 0.87 | ACHE (0.46) | TUBB1ACHECYP3A4MAPTCA9 | |
| SCHEMBL448336 | 0.85 | ALDH1A1 (0.39) | TUBB1ACHECYP3A4MAPTCA9 | |
| SCHEMBL11160603 | 0.81 | ACHE (0.41) | TUBB1ACHECYP3A4MAPTCA9 | |
| SCHEMBL8093719 | 0.80 | TUBB1 (0.44) | TUBB1ACHECYP3A4MAPTALDH1A1 | |
| SCHEMBL5704438 | 0.80 | ALDH1A1 (0.39) | TUBB1ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL17087196 | 0.79 | ACHE (0.44) | TUBB1ACHECYP3A4MAPTCA9 | |
| SCHEMBL6063053 | 0.78 | TUBB1 (0.38) | TUBB1ACHECYP3A4MAPTCA9 | |
| SCHEMBL9958699 | 0.78 | PTPN1 (0.35) | TUBB1ALDH1A1PTGS2 | |
| Bromide SCHEMBL29739052 | 0.78 | TUBB1 (0.42) | TUBB1CYP3A4MAPTALDH1A1HTR2A | |
| SCHEMBL28963943 | 0.77 | NPC1 (0.42) | TUBB1ACHECYP3A4MAPTCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |