Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195019 | 1.00 | NAMPT (0.58) | NAMPTHTTALDH1A1TUBBTDP1 | |
| SCHEMBL8220319 | 0.82 | LMNA (0.47) | NAMPTHTTALDH1A1TDP1 | |
| SCHEMBL7978261 | 0.81 | NAMPT (0.55) | NAMPT | |
| SCHEMBL7979965 | 0.80 | NAMPT (0.45) | NAMPTHTTALDH1A1TUBB | |
| SCHEMBL14322992 | 0.76 | NAMPT (0.49) | NAMPTALDH1A1 | |
| SCHEMBL8195014 | 0.76 | HTT (0.54) | NAMPTHTTALDH1A1TDP1CES1 | |
| SCHEMBL8195508 | 0.76 | HTT (0.54) | NAMPTHTTALDH1A1TDP1CES1 | |
| SCHEMBL12335073 | 0.75 | NAMPT (0.93) | NAMPTHTTALDH1A1 | |
| SCHEMBL7978003 | 0.75 | NAMPT (0.46) | NAMPTALDH1A1 | |
| SCHEMBL7978005 | 0.75 | NAMPT (0.46) | NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | claimed |
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |