Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521166 | 0.85 | PTGDR2 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2APPARD | |
| SCHEMBL7962805 | 0.84 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2APPARA | |
| SCHEMBL7524434 | 0.74 | TP53 (0.41) | ALDH1A1PPARAPPARDMAPTPOLB | |
| SCHEMBL7976487 | 0.74 | PPARA (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2APPARA | |
| SCHEMBL7527946 | 0.73 | PPARD (0.39) | PPARAPPARD | |
| SCHEMBL7522034 | 0.72 | PTGIR (0.43) | MEN1KMT2APPARAPPARDPPARG | |
| SCHEMBL7526679 | 0.71 | FFAR1 (0.38) | ALDH1A1MEN1KMT2APPARDPPARG | |
| SCHEMBL7555841 | 0.70 | PTGIR (0.43) | SMN1; SMN2PPARAPPARD | |
| SCHEMBL7526347 | 0.70 | PTGIR (0.43) | ALDH1A1MEN1KMT2APPARAPPARD | |
| SCHEMBL7976488 | 0.70 | MEN1 (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |