Sugi Predict

Sugi Predict / Compounds / SCHEMBL7976544

SCHEMBL7976544

SCHEMBL7976544

Oc1ccc(Br)cc1CBr

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 2/20 0.52
▸ TSHR P16473 2/20 0.52
▸ GFER P55789 1/20 0.52
▸ ALDH1A1 P00352 4/20 0.49
▸ HPGD P15428 3/20 0.49
▸ CYP1A2 P05177 2/20 0.49
▸ CYP2C9 P11712 2/20 0.49
▸ HTT P42858 2/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ PKM P14618 1/20 0.49
▸ HIF1A Q16665 1/20 0.49
▸ CASP1 P29466 2/20 0.45
▸ CES2 O00748 1/20 0.45
▸ GALR3 O60755 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ CA12 O43570 2/20 0.44
▸ CA1 P00915 2/20 0.44
▸ CA2 P00918 2/20 0.44
▸ CA9 Q16790 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15299051 0.84 ALDH1A1 (0.51) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL7973148 0.84 ALDH1A1 (0.49) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL68224 0.83 ALOX15 (0.54) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL25335 0.81 ALOX15 (0.52) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL29870381 0.81 ALOX15 (0.52) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL11453783 0.79 ALOX15 (0.50) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL82273 0.79 ALDH1A1 (0.54) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL2743858 0.79 ALOX15 (0.50) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL14496519 0.79 ALOX15 (0.50) ALOX15TSHRGFERALDH1A1HPGD
SCHEMBL30396162 0.79 ALDH1A1 (0.54) ALOX15TSHRGFERALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110746345-B Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine 苏州永健生物医药有限公司 2022-03-04 — — CN claimed
CN-110746345-A Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine 苏州永健生物医药有限公司 2020-02-04 — — CN claimed
CN-119798149-A Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 宜昌天睿生物医药有限责任公司 2025-04-11 — — CN disclosed
CN-115322144-B Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 上海药坦药物研究开发有限公司 2024-05-24 — — CN disclosed
CN-116751157-A Amplified preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 上海再启生物技术有限公司 2023-09-15 — — CN disclosed
CN-115322144-A Preparation method of 2- (2-amino-5-bromo-benzoyl) pyridine 上海药坦药物研究开发有限公司 2022-11-11 — — CN disclosed
CN-110746345-B Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine 苏州永健生物医药有限公司 2022-03-04 — — CN disclosed
CN-110746345-B Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine 苏州永健生物医药有限公司 2022-03-04 — — CN disclosed
CN-110746345-A Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine 苏州永健生物医药有限公司 2020-02-04 — — CN disclosed
CN-110746345-A Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine 苏州永健生物医药有限公司 2020-02-04 — — CN disclosed
CN-107106526-A For organize selfreparing and regeneration be substituted aromatic compounds and pharmaceutical composition 普罗米蒂克医药SMT有限公司 2017-08-29 — — CN disclosed
CN-106999458-A Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of diabetes 普罗米蒂克医药SMT有限公司 2017-08-01 — — CN disclosed
CN-106999456-A substituted aromatic compounds and pharmaceutical composition for preventing and treating osteoporosis 普罗米蒂克医药SMT有限公司 2017-08-01 — — CN disclosed
WO-2001090105-A1 ISOTHIAZOLES AS PESTICIDES SYNGENTA LIMITED (GB) 2001-11-29 — — WO disclosed