SCHEMBL30396162

SCHEMBL30396162

CCc1cc(Br)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 1/20 0.54
POLB P06746 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ESR1 P03372 4/20 0.53
ESR2 Q92731 4/20 0.53
HPGD P15428 2/20 0.51
HTT P42858 1/20 0.51
ALOX15 P16050 2/20 0.50
TSHR P16473 2/20 0.50
BACE1 P56817 1/20 0.50
GFER P55789 1/20 0.50
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CES2 O00748 1/20 0.48
GALR3 O60755 1/20 0.48
CASP1 P29466 1/20 0.48
CYP2C19 P33261 1/20 0.48
CYP3A4 P08684 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82273 1.00 ALDH1A1 (0.54) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
SCHEMBL6428557 0.90 ALDH1A1 (0.48) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
SCHEMBL574298 0.83 ALOX5 (0.50) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
SCHEMBL28145390 0.82 ALDH1A1 (0.51) ALDH1A1KDM4EPOLBSMN1; SMN2HPGD
SCHEMBL1005997 0.82 ALOX15 (0.44) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
SCHEMBL30777878 0.82 ALOX15 (0.44) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
SCHEMBL68224 0.81 ALOX15 (0.54) ALDH1A1KDM4EPOLBSMN1; SMN2HPGD
SCHEMBL4813970 0.81 ALDH1A1 (0.61) ALDH1A1KDM4EPOLBSMN1; SMN2HPGD
SCHEMBL1821570 0.79 HPGD (0.47) ALDH1A1KDM4EPOLBSMN1; SMN2HPGD
SCHEMBL573894 0.79 TYR (0.52) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694889-A1 COMPOUNDS AND METHODS FOR TREATING PROTEIN AGGREGATION DISEASES Acelot, Inc. (US) 2026-02-18 EP disclosed
US-12304907-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-05-20 US disclosed
EP-4551195-A1 CANNABINOID LIPID PREMIXTURE Fertin Pharma A/S (DK) 2025-05-14 EP disclosed
WO-2025067622-A1 CANNABIDIOL FOR USE IN ALLEVIATING XEROSTOMIA FERTIN PHARMA A/S (DK) 2025-04-03 WO disclosed
EP-3769624-B1 ENHANCING THE ANTIMICROBIAL ACTIVITY OF BIOCIDES WITH POLYMERS BASF SE (DE) 2024-10-30 EP disclosed
WO-2024216203-A1 COMPOUNDS AND METHODS FOR TREATING PROTEIN AGGREGATION DISEASES ACELOT, INC. (US) 2024-10-17 WO disclosed
US-20240279219-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2024-08-22 US disclosed
WO-2024008261-A1 CANNABINOID LIPID PREMIXTURE FERTIN PHARMA A/S (DK) 2024-01-11 WO disclosed
US-11666050-B2 Enhancing the antimicrobial activity of biocides with polymers BASF SE (DE) 2023-06-06 US disclosed
US-11647746-B2 Enhancing the antimicrobial activity of biocides with polymers BASF SE (DE) 2023-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647746-B2 Enhancing the antimicrobial activity of biocides with polymers CAT, AOC1, DDT ALDH1A1 787/4885KDM4E 2071/4885POLB 92/4885
US-20240279219-A1 COMPOUNDS AND METHODS OF USE F12, C1R, ABCG2 ALDH1A1 128/4885KDM4E 3895/4885POLB 3098/4885
US-11666050-B2 Enhancing the antimicrobial activity of biocides with polymers CAT, AOC1, DDT ALDH1A1 787/4885KDM4E 2071/4885POLB 92/4885
US-12304907-B2 Compounds and methods of use F12, C1R, ABCG2 ALDH1A1 128/4885KDM4E 3895/4885POLB 3098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.