Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 14/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.46 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976654 | 1.00 | FKBP1A (0.53) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7251418 | 0.85 | FKBP1A (0.65) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7980034 | 0.81 | FKBP1A (0.73) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7980032 | 0.81 | FKBP1A (0.73) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7980405 | 0.80 | FKBP1A (0.73) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7980403 | 0.80 | FKBP1A (0.73) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7976989 | 0.80 | FKBP1A (0.71) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7980598 | 0.78 | FKBP1A (0.61) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7980600 | 0.78 | FKBP1A (0.61) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7978561 | 0.75 | MMP9 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323215-B1 | TREAT AND PREVENT DISORDERS CHARACTERIZED BY NEURONAL DAMAGE SUCH AS PARKINSON'S DISEASE, ALZHEIMER'S DISEASE, STROKE, MULTIPLE SCLEROSIS, AMYOTROPHIC LATERAL SCLEROSIS, DIABETIC NEUROPATHY AND BELL'S PALSY. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-11-27 | — | — | US | disclosed |