Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950528 | 0.89 | STAT3 (0.43) | DRD2DRD1DRD3DRD4DRD5 | |
| SCHEMBL24261197 | 0.82 | OPRK1 (0.55) | DRD2DRD1TAAR1DRD3CHRM2 | |
| SCHEMBL3631399 | 0.82 | TAAR1 (0.52) | TAAR1 | |
| SCHEMBL7794272 | 0.82 | DRD2 (0.61) | DRD2DRD1TAAR1DRD3CHRM2 | |
| SCHEMBL15178073 | 0.81 | ENPP2 (0.48) | DRD2DRD1TAAR1DRD3CHRM2 | |
| SCHEMBL11593827 | 0.81 | CHRM2 (0.59) | DRD2DRD1TAAR1DRD3CHRM2 | |
| SCHEMBL13537805 | 0.81 | ENPP2 (0.48) | DRD2DRD1TAAR1DRD3CHRM2 | |
| SCHEMBL27945060 | 0.81 | DRD1 (0.53) | DRD2DRD1TAAR1DRD3CHRM2 | |
| SCHEMBL4572701 | 0.81 | NPC1 (0.57) | TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL104012 | 0.79 | OPRK1 (0.70) | DRD2DRD1TAAR1DRD3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| US-5374629-A | A triene steroids as anticarcinogenic agents, treating skin disorders | LEO PHARMACEUTICAL PRODUCTS LTD. A/S LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1994-12-20 | — | — | US | disclosed |
| EP-0522013-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1994-11-23 | — | — | EP | disclosed |
| EP-0522013-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991015475-A1 | NOVEL VITAMIN D ANALOGUES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1991-10-17 | — | — | WO | disclosed |