Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965208 | 0.87 | MEN1 (0.41) | ALDH1A1LMNAHTR2AHTR2CHTR2B | |
| SCHEMBL12679302 | 0.84 | TSHR (0.45) | KMT2AMAPTMEN1 | |
| SCHEMBL28628435 | 0.75 | HTR2A (0.57) | ALDH1A1LMNAHTR2AHTR2CHTR2B | |
| SCHEMBL22335132 | 0.73 | NPC1 (0.57) | ALDH1A1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL9271312 | 0.71 | PLA2G6 (0.44) | ALDH1A1HPGD | |
| SCHEMBL2934674 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL2934676 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL2934678 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL16142353 | 0.70 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL13039624 | 0.69 | TSHR (0.46) | LMNAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |