Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976878 | 0.87 | ALDH1A1 (0.42) | MEN1KMT2APOLBLMNARECQL | |
| SCHEMBL7978624 | 0.75 | SMN1; SMN2 (0.37) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL85535 | 0.71 | MEN1 (0.64) | MEN1KMT2APOLBLMNARECQL | |
| SCHEMBL12679302 | 0.70 | TSHR (0.45) | MEN1KMT2AMAPT | |
| SCHEMBL8715237 | 0.69 | CYP2C9 (0.47) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL7614274 | 0.69 | CYP2C9 (0.38) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL19025562 | 0.69 | MEN1 (0.62) | MEN1KMT2APOLBLMNARECQL | |
| Fluoride SCHEMBL27503363 | 0.69 | MEN1 (0.62) | MEN1KMT2APOLBLMNARECQL | |
| SCHEMBL1583098 | 0.68 | TSHR (0.46) | MEN1KMT2APOLBLMNARECQL | |
| SCHEMBL1022578 | 0.68 | TSHR (0.46) | MEN1KMT2APOLBLMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |