Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177969 | 0.81 | KDM4E (0.53) | KDM4EL3MBTL1LMNATDP1CYP1A2 | |
| SCHEMBL28139433 | 0.78 | BRD4 (0.39) | ALDH1A1KDM4EADORA2AL3MBTL1LMNA | |
| SCHEMBL7784447 | 0.78 | TDP1 (0.44) | ALDH1A1KDM4EAPOBEC3GRAB9ALMNA | |
| SCHEMBL7525447 | 0.77 | ADORA2A (0.40) | ALDH1A1KDM4EADORA2ALMNAPKM | |
| SCHEMBL2557632 | 0.77 | EPHX1 (0.43) | ALDH1A1KDM4ELMNACYP1A2MEN1 | |
| SCHEMBL4777973 | 0.77 | KDM4E (0.50) | ALDH1A1KDM4EADORA2AL3MBTL1RAB9A | |
| SCHEMBL1554320 | 0.76 | KDM4E (0.53) | ALDH1A1KDM4EL3MBTL1LMNATDP1 | |
| SCHEMBL12869882 | 0.76 | LMNA (0.55) | ALDH1A1KDM4EAPOBEC3GRAB9ALMNA | |
| SCHEMBL7353766 | 0.76 | KMT2A (0.51) | KDM4EL3MBTL1RAB9ALMNAKMT2A | |
| SCHEMBL2555729 | 0.75 | KCNA5 (0.51) | ALDH1A1KDM4EADORA2ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082307-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 2-SUBSTITUTED PIPERIDINE STEREOISOMERS | CELGENE CORPORATION (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999061425-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 2-SUBSTITUTED PIPERIDINE STEREOISOMERS | CELGENE CORPORATION (US) | 1999-12-02 | — | — | WO | disclosed |