Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702236 | 0.90 | CTSK (0.53) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL30312666 | 0.90 | CTSK (0.53) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL7700364 | 0.84 | MEN1 (0.51) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL7974820 | 0.84 | MEN1 (0.51) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL7977002 | 0.83 | CTSK (0.46) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL7963473 | 0.81 | CTSS (0.45) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL16924919 | 0.81 | CTSK (0.51) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL30312609 | 0.80 | CTSS (0.56) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL13702232 | 0.80 | CTSS (0.56) | CTSKCTSSCA1CA2CAPN1 | |
| SCHEMBL10144100 | 0.80 | CTSS (0.51) | CTSKCTSSCA2CAPN1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |