SCHEMBL7977031

SCHEMBL7977031

N=CCNCCCCC(N)C(=O)OCCc1ccc(CCOC(=O)C(N)CCCCNCC=N)cc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.38
CA2 P00918 7/20 0.38
CA12 O43570 4/20 0.38
CA9 Q16790 4/20 0.38
SPHK1 Q9NYA1 4/20 0.36
CTSK P43235 1/20 0.36
DPP8 Q6V1X1 2/20 0.35
DPP7 Q9UHL4 2/20 0.35
DPP9 Q86TI2 1/20 0.35
MARS1 P56192 1/20 0.32
LTA4H P09960 1/20 0.32
SPHK2 Q9NRA0 1/20 0.32
MET P08581 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7963555 0.88 CA1 (0.41) CA1CA2CA12CA9
Hydrochloric Acid SCHEMBL7975014 0.81 DPP8 (0.47) DPP8DPP7DPP9LTA4H
SCHEMBL7977030 0.79 CA1 (0.47) CA1CA2CA12CA9DPP8
SCHEMBL7973817 0.78 CA2 (0.37) CA1CA2CA12CA9
SCHEMBL7974904 0.78 DPP7 (0.35) CA1CA2CA12CA9DPP8
SCHEMBL7963487 0.74 CA12 (0.41) CA1CA2CA12CA9
SCHEMBL7974865 0.74 CA12 (0.41) CA1CA2CA12CA9
SCHEMBL934762 0.73 GSR (0.48)
SCHEMBL6130709 0.73 DPP7 (0.34) DPP8DPP7DPP9LTA4H
SCHEMBL7974900 0.73 GSR (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001005748-A1 OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS MONSANTO COMPANY (US) 2001-01-25 WO disclosed