SCHEMBL7977030

SCHEMBL7977030

CC(=N)NCCCCC(N)C(=O)OCCc1ccc(CCOC(=O)C(N)CCCCNC(C)=N)cc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.47
CA2 P00918 7/20 0.47
CA12 O43570 6/20 0.47
CA9 Q16790 6/20 0.47
ALB P02768 1/20 0.38
DPP8 Q6V1X1 2/20 0.37
DPP7 Q9UHL4 1/20 0.37
MARS1 P56192 1/20 0.37
NPY1R P25929 1/20 0.37
NPY4R P50391 1/20 0.37
DPP9 Q86TI2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7963550 0.88 CA1 (0.48) CA1CA2CA12CA9
Hydrochloric Acid SCHEMBL7975011 0.80 DPP8 (0.53) DPP8DPP7DPP9
SCHEMBL7974902 0.79 DPP7 (0.44) CA1CA2CA12CA9DPP7
SCHEMBL14090886 0.79 DPP7 (0.44) CA1CA2CA12CA9DPP7
SCHEMBL7973813 0.79 CA2 (0.43) CA1CA2CA12CA9
SCHEMBL7977031 0.79 CA1 (0.38) CA1CA2CA12CA9DPP8
SCHEMBL8080773 0.78 GNAI3 (0.46) CA1CA2CA12CA9DPP7
SCHEMBL7911960 0.78 DPP7 (0.42) CA1CA2CA12CA9DPP8
SCHEMBL2717436 0.76 DPP7 (0.41) CA1CA2CA12CA9DPP8
SCHEMBL12619397 0.74 DPP7 (0.41) CA1CA2CA12CA9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001005748-A1 OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS MONSANTO COMPANY (US) 2001-01-25 WO disclosed